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Vet’s Best Hot Spot Dog Shampoo (16 oz) has a natural formula that provides fast relief for itchy, dry, and irritated skin. We use Tea Tree Oil, Aloe Vera, and Chamomile as our main natural ingredients to soothe and heal red, inflamed dog skin due to itching and scratching. Hot Spot dog shampoo for itchy skin is alcohol-free and safe to use with puppies 12 weeks or older.